SF3B1: hotspot mutazionale nei prolattinomi
نویسندگان
چکیده
منابع مشابه
SF3B1 mutations in chronic lymphocytic leukemia.
SF3B1 is a critical component of the splicing machinery, which catalyzes the removal of introns from precursor messenger RNA (mRNA). Next-generation sequencing studies have identified mutations in SF3B1 in chronic lymphocytic leukemia (CLL) at high frequency. In CLL, SF3B1 mutation is associated with more aggressive disease and shorter survival, and recent studies suggest that it can be incorpo...
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ژورنال
عنوان ژورنال: L'Endocrinologo
سال: 2021
ISSN: ['1590-170X', '1720-8351']
DOI: https://doi.org/10.1007/s40619-021-00878-5